Kidney Diseases:
Acute toxicity
Agent None Numerous toxieants and drugs may cause renal pathology.
Hosts All.
Location Primarily proximal tubules, but other components may also be affected.
Type of lesion Vacuolation and degeneration of tubular epithelial cells. Interstilial haemorrhage.
Special features Granulomas with casous centres may also be seen in gastric mueosa and gut wall. Similar lesions are seen in the condition ealled visceral granuloma in several species.
Diagnosis History, characteristic hislopathological lesion. Absence of infectious agents.


Degeneration of tubular epithelial cells in red morwong exposed to sewage.

Eosinophilic droplets in tubular epithelium as
a result of exposure to heavy metals.

Needle-like oxalate crystals in kidney tubules of koi carp.

Ethylene glycol toxicity in koi carp.