Bacterial kidney disease (BKD), Dee disease
Agent	Renibacterium salmoninarum (Gram +)
Hosts	Salmonids.
Location	Primarily kidney interstitium with secondary involvement of the nephron (route of infection probably important!), other organs may also be affected.
Type of lesion	Chronic, granulomatous or pyogranulomatous, sometimes with caseation and cultivation. Macrophages and neutrophils dominate the inflammatory process and are often full of the causative bacterium.
Special features	Intracellular.
Diagnosis	Gram staining (+), PAS, Immunohistochemistry. Differential diagnosis include mycobacterial infections and fungal nephritis.

Granulomatous response characteristic of bacterial kidney disease.

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